Chemistry - Ph.D. / Sc.D.
Recent Submissions
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Development of a reactive peptide sequence for site-selective bioconjugation ?
(Massachusetts Institute of Technology, 2020)Achieving catalyst-free, site-selective modification of proteins in water is a significant challenge in chemical biology. Issues of residue specificity, site-selectivity, reagent stability, and reaction rate are pervasive ... -
Palladium catalyzed cross-coupling of esters and amides ?
(Massachusetts Institute of Technology, 2019)Over the last 40 years, great strides have been made in the use of palladium as both a catalyst and a reagent for a multitude of chemical transformations that have had tremendous impacts all walks of life from material ... -
Palladium- and nickel-catalyzed C-N cross-coupling reactions featuring soluble organic bases ?
(Massachusetts Institute of Technology, 2020)Chapter 1: Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common Soluble Base in C-N Coupling Due to the low intrinsic acidity of amines, palladium-catalyzed C-N cross-coupling ...
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